The Pitfalls Of Obesity Treatment

While scoring high on Total Body Weight Loss (TBWL%), gold-standard bariatric treatments are avoided by most patients and insurers, as these treatments are highly-invasive, may lead to significant adverse events, and often involve irreversible GI tract reconfigurations. In consequence, they are performed in less than 1% of the eligible population.

Alternatives such as intra-gastric balloons, while utilizing safer trans-oral access and being covered for lower-BMI patients, are temporary and achieve lower TBWL%. Endoscopic gastroplasty, which does provide much higher TBWL%, is an extremely cumbersome procedure that is generally inaccessible to patients and physicians alike.

EndoZip™
An Automated Stitch In Time

EndoZip is a fully automated, operator independent and minimally invasive robotic suturing system,
that safely delivers durable and effective restrictive sutures to the stomach wall.

Shape & Zip. It’s As Simple As That.

Introduce

Introduce

Trans-oral endoscopic access and positioning directly in the designated area of restriction

shape

Shape

Accurate grasping and stitching of the stomach tissue from within

zip

Zip

Helical needle is activated automatically to connect the stomach walls and secure them with a continuous suture

Remove

Remove

Smooth system removal

Watch Procedure Demo

Simple, Reproducible Procedures

Making safe and effective endoscopic weight-loss treatments accessible to both patients and their physicians.

Simple, Reproducible Procedures

Consistent Suture Size And Depth

Simple, Reproducible Procedures

High Suture
Density

Simple, Reproducible Procedures

High Suture
Durability

Simple, Reproducible Procedures

Safe and Longer Lasting Effect

Simple, Reproducible Procedures

Operator
Independent

Simple, Reproducible Procedures

Reproducible
Results

Simple, Reproducible Procedures

Ease Of Use With A
Short Learning Curve

Simple, Reproducible Procedures

Suitable For All Levels of Physician Experience

Clinical Status

Ongoing

An ongoing multi-center pilot study was launched on July 2021 with 45 patients. The study is
showing extremely promising results, demonstrating the high safety profile, very short learning
curve and excellent usability of our robotic suturing system.

Completed

Nitinotes has recently completed its FIH study in Spain. Led by Dr. Lopez Nava,
Director of the Bariatric Endoscopy Unit at HM Sanchinarro University Hospital, Madrid.

0
Patients
0%
%TBWL after 6 months
0%
Procedure success

To see a full summary of the study

Download PDF

About Nitinotes

Nitinotes is a privately-held medical device company based in Caesarea Israel. Its flagship product EndoZip is a novel robotic endoscopic suturing system for safer and simpler gastroscopic restriction for the treatment of obesity. Backed by preclinical success and prominent KOLs, Nitinotes’s fully automated, minimally invasive gastroscopic suturing system provides an effective solution to class 1 and 2 obesity patients, for the majority of whom gold-standard bariatric surgery is uncovered and/or inadvisable.

Nitinotes has completed, in late 2019, its FIH study in Spain, demonstrating a high safety profile with no AE related to the procedure, and achieving promising efficacy results.
An ongoing multi-center pilot study was launched on July 2021 with 45 patients. The study is showing extremely promising results, demonstrating the high safety profile, very short learning curve and excellent usability of our robotic suturing system.

Nitinotes is headed by a team of R&D
and business experts, including:

Raz Bar-On

BSc, MBA

CEO

Irit Yaniv

MD, MBA

Executive Chairwoman

Tal Yered

BSc, MSc

VP R&D

Hagit Ephrath

MA

COO, Regulatory Affairs

Actively Supported by

accelmed
mtip
elron

Contact Us

Nitinotes Surgical Ltd. • 5 Haeshel st, Beit Galileo 2,  P.O Box 3158, Caesarea 3079815, Israel • Tel: +972-4-8876698 • website@nitinotesurgical.com